Neurobiology of Alcohol Use and Alcohol-Induced Organ Damage
Neurobiology of Alcohol Use and Alcohol-Induced Organ Damage
Pricing
Information
Date & Time
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Description
This session will provide an overview of the genetic, epigenetic, neurobiological, developmental, and clinical factors that contribute to alcohol use and alcohol-associated liver disease (ALD). Dr. Nisar will discuss the role of genetics and epigenetics in ALD, with particular emphasis on alcohol-induced epigenetic alterations, including DNA methylation changes mediated by epigenetic enzymes, and how these changes drive disease progression from steatosis to fibrosis and cirrhosis, as well as the broader systemic effects of hepatic dysfunction on other organs. Dr. Mangieri will present an overview of the brain structures and neurotransmitter systems affected by alcohol use. Dr. Silveri will review findings from human neuroimaging studies demonstrating how developmental changes in adolescent brain systems contribute to vulnerability to the initiation of alcohol use and increased risk for addiction later in life. Dr. Rouzer’s portion of this module will provide an overview of Fetal Alcohol Spectrum Disorders (FASD), including prevalence, core neurobehavioral characteristics, and practical considerations for recognizing and responding to FASD in clinical and service settings.
Learning Objectives
Participants will be able to:
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Describe key neurobehavioral characteristics associated with fetal alcohol spectrum disorders (FASD) and recognize situations in which referral for further evaluation may be appropriate.
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Identify epigenetic mechanisms (DNA methylation) altered by chronic alcohol consumption and explain their role in promoting hepatic inflammation and fibrosis.
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Recognize key brain regions and molecular targets affected by alcohol and describe how alcohol influences the major neurotransmitter systems in the brain.
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Define how human neuroimaging findings identify frontolimbic brain systems that contribute to vulnerability for alcohol use during adolescence.
Educational Goal
Target Audience
- Addiction Professional
- Counselor
- Marriage & Family Therapist
- Psychologist
- Social Worker
Presenters
Financially Sponsored By
- Research Society on Alcohol