Live Webinar
From Morphine to Orphines: Tracking the Next Generation of Synthetic Opioids
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From Morphine to Orphines: Tracking the Next Generation of Synthetic Opioids
1.0 CE Hours
Introductory
$0
References
References
- Marchei, E., Graziano, S., Pichini, S., & Farré, M. (2026). Brorphine and its analogues: Pharmacology, toxicology, and biomonitoring. Therapeutic Drug Monitoring, 48(4), 424–431. https://doi.org/10.1097/FTD.0000000000001446
- Vandeputte, M. M., Bilel, S., Tirri, M., Corli, G., Bassi, M., Layle, N. K., Fantinati, A., Walther, D., Iula, D. M., Baumann, M. H., Stove, C. P., & Marti, M. (2024). Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization. Neuropharmacology, 260, 110113. https://doi.org/10.1016/j.neuropharm.2024.110113
- Kusko, R., Liss, D., House, S. L., House, S. B., Krotulski, A., & Aldy, K. (2026). An emerging synthetic opioid in the drug supply: A case of opioid overdose with biological confirmation of cychlorphine. Journal of Medical Toxicology. https://doi.org/10.1007/s13181-026-01146-4
- Dugues, P., Robin, T., Bellouard, M., Chenorhokian, S., Triguel, M., Pfau, G., Feng, C., Cherki, S., Herbette, G., Alvarez, J. C., & Larabi, I. A. (2026). Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: First detection in Europe. Clinical Chemistry and Laboratory Medicine, 64(6), 1413–1424. https://doi.org/10.1515/cclm-2025-1428
- Vandeputte, M. M., & Stove, C. P. (2025). Navigating nitazenes: A pharmacological and toxicological overview of new synthetic opioids with a 2-benzylbenzimidazole core. Neuropharmacology, 275, 110470. https://doi.org/10.1016/j.neuropharm.2025.110470
- Krotulski, A. J., Papsun, D. M., Noble, C., Kacinko, S. L., & Logan, B. K. (2021). Brorphine: Investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography-mass spectrometry. Journal of Forensic Sciences, 66(2), 664–676. https://doi.org/10.1111/1556-4029.14623