Social, family, and cultural backgrounds determine how we experience mental health, communicate symptoms, which healthcare interventions we prefer, and the support we get from family and friends. Culture, therefore, plays a significant role in mental health needs and expectations, especially as societies are becoming more multicultural. In a world where change is the only constant, we should also acknowledge that one size doesn’t fit all in mental health. Dr. Mouton explores how to design and deliver culturally-informed care in daily practice for addiction care and psychiatry, in particular, the effect of culture on addiction, ADHD and other co-occurring mental health challenges.